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GLP-1 receptor agonists mimic gut hormones to curb appetite and slow digestion, a mechanism driving the success of therapies from Novo Nordisk (Ozempic for diabetes and Wegovy for weight loss) and Lilly (Mounjaro for diabetes and Zepbound for weight loss)

It appears to protect kidney function by improving blood glucose control, reducing inflammation, and potentially lessening protein loss in urine, which is a key indicator of kidney stress

It mimics natural signals and activates melanocortin receptorsessential switches that help turn on sexual desire

In contrast, genes affected by CHRM3 and NCSTN overexpression were more prominently enriched in antigen processing and presentation, MHC class II complex, lysosomal membrane, secretory granule, MHC protein complex binding, and peptide binding, suggesting potential involvement in antigen presentation and immune-related processes